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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f1935ca0028149271d22996a3f2a9a1eca001f738dd6241014263f35764d2dd' 
  AND token = '6CPjkxKOA6dkRDA3+RNzz1ZsS0TiAxbeNQGxxP3+As8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}