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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec6289eb235bc09197ea60d5956ad7aaf9db2cf9507c348c1ad94f7e3a988881' 
  AND token = 'TVG1hbUAqiNi/hMT4LECXRsSg8H2xbOoYPAtmqF3GqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}