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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffa19654f9ba1446cc2c63e52285541222090f980ecb734ecfa242a880a06fd6' 
  AND token = 'sClZXpbD7QaGJnlxYrcbbdrTW+5VW3WJZ1YKMrhDQxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}