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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a55ff46d7a6062bf3429a992c87c692068f1a28e545e6e271ec30d657a30774' 
  AND token = '+WgDLKuNQH3f8pZFLuueD21ofjwlxMhtn4i+yW/4TwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}