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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd675e7fd49a799bcbfd0511fae22fbae4816739d50139b4e610efcd804743503' 
  AND token = '6fOqPab9OebiAvL6Yw4c1Srmc56as4q2cogY3viqISM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}