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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b15de93145a75a9786799976fc2ef6899ddbfc89724af0be89881f5289799a' 
  AND token = 'aEhUNTWRmB+AGTWnhMLw3AS5COwoAiNG2tnPYGTogF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}