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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1852819abde1efaced8a5c7cadc7f768341a07fdfc8bca0417fa340cd0f6c69d' 
  AND token = 'G4ZrU00zYNxFHfvy9CKhs2/r/sXNHWzIqvzS6S8s4KQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}