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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce8c963265ebc80583b53d09e3f58f30e3a15a14a4ef5d1f68db256f8663b534' 
  AND token = 'poVG6SBSKTeEsjtnsAJVFRzSBQe2lETC+WRPi3T3JwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}