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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2824cc43e911d4201244848373479ef4c144242b161655643af1d9acc3f7867' 
  AND token = 'n2UAH5gLKCCUAhpxko+GY79eL6aRBXF+HLQmxgJc4yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}