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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41ff3801ac762ca51000908b420b1a07c14313ca126806b05cb082ee359a88bb' 
  AND token = 'vA8orUzTah/HWaC8pZ44t2AEzEyEnR2sQTjGiFCp49g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00235

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}