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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '530c49bbf1f8d69fbc44b8237f42479177ddc782b8aec1c294b1650b3f718da6' 
  AND token = '+55ZX2Y9L/bdUj0541Se7FcANFI1AnmwjPjD5e2C0IY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}