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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e570cb1fd2907637b9f55b0a63fa8fd97f7f89fe50643552092726802057470d' 
  AND token = 'JfykPoAvPzV9CqgdpEih65xJaY/bcAc7ygILkXaAfBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}