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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2608123cf3de3804ac340bb17c65e0894ec3a8b9f1a5ac5f5cfea071d533c911' 
  AND token = 'B8Tf3yyaDgXH7I55JUNXLRHsLlOEaQRKUE2Ubt98pQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}