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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e40cf8a8a0b0a7555eda872470fdc54615d6aaf11ac8ee69806bcb20008dab9' 
  AND token = 'CAC0pSaQ3HOYh40JkprOeDyvh5pLPZgAe+TvuZwqYEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}