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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '729e923b235bb0fbc4c27ac94918003ed2ce03c1bb0ae62736f1d3ca3dbffdff' 
  AND token = 'Ddk3XdxTRBFcdvnXxY1Srr6FtgQk63K0v7EsPYP6aus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}