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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8501d55c324b508aa1c899a7fe162b9cf7bb1bf2042a7fcfd95d1ef4166200bd' 
  AND token = 'fDVQKy6ubCbcNpkU9eM8DixA5Lz+jawmO2lS5Qpg64g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}