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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09767e3e22c1ac3a2ff9a9c02807cb54749006e4b681135bb7222729b1e01a5c' 
  AND token = 'QROGxo73aEkZKqIWNfbR+UdglDC0GjJNg3zikZobbkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}