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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65d2d52cb84f7c982752645f7261c96b121292a8f3d7696537f08a9eb8eb44c4' 
  AND token = '6rKV0u5FxnS4BgRZbUEaC6X7h2U94kpBwgGKRaYBS9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}