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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd116915c6d34cd2b9bfebcb2d22676dd4b0dc2f0a812a002f8647395343157a0' 
  AND token = 'mv65MkpTw0YEPsph6DcRDAXvBJHSfkUBKgMy0B8tHc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}