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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd53c6b4bd78287186ea877f4b490154e32756239a45df46bbb421b7c18cf07de' 
  AND token = 'Sh/zTTkbhWxBSqjm8tMNDb5irA/gu/2q72Ipgi+U3x8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}