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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b2512e649a7718e3ea3e8203c10d0ad930ebc54423365b0f0b716933e2e44da' 
  AND token = '9VfSDwlh3GtwtUlgzE0nU2qvJHPg2x4xmr/1nGNKs1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}