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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '013e736b772cb98d2ee0a658f3fa661d48d4beb4b06729a8518120487e693be4' 
  AND token = 'VV0++/t6CsRnwPmEBsYVHekLtavMh4WCYlvwK8v79nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}