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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cefb1e1a8506cde626c890a215ee34a087ceec2d46f8fea8833b2cda9a9b909' 
  AND token = 'KDoUQJPy8PUwFSzNc2VZDS2b13I7/XwJEF9gJJKhehc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}