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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab82f8adef8b7ce34d13993de509a5ccbd53ba343c04d8828a8ae4b4209ff2b3' 
  AND token = 'UpgY9g2Ajp0tOQsHaHMT5UcYil4gtDXlOph39n9fLAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}