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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd889d3b37e57dfe54a3ab3ca87ec46d2a730980071c8843a8e8b50504da2694b' 
  AND token = 'wN5MzdnEcMloKGmxsQFqo2W/Ge1uFSiyQOQotipIwyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}