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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94e3a5df5464c6769da956a5f75b06d010d5edbf1f4b18a79375bb4c0622c159' 
  AND token = 'ThCD3xAtcdmezdyehrebYcKft6CMwLqXGc7nza84y6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}