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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72bf10791a1e59699a4dd18d2280161062a3c629df91537f2b4d00e12a65391d' 
  AND token = 'KWWUrpeI6BT1T/LmrMusDbzDeup83JjFWEg6Ex5BwN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}