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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aed3047fbbe5a4706af11ffbce4870b6000e5052cc4b84d91bc12f4a2b482b33' 
  AND token = 'lAnZ7AnmuQElZtvm8sept0WIXqjCIHgh8pq2yW6/z0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}