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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef5b2d3a0633833074e19fb7e368adb1542dacbe9447818de2519c9261a1496d' 
  AND token = '6C2lJ3OaW+gZRdwvWXku3/VnDYX5ycEIJLXWKA2VN98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}