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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0325532288f00e25f51a44530bb8c38c7f70002b035e0b56b68f1481c70366ca' 
  AND token = '/Ee1vqvx/Uwke7lZW0c3Q/6lyuc8BD8Nx3jOEnO/8EY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}