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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb53e8597056aa4c87945e9b35345d8cc75cbf4a1f147103f666dd8e52810a15' 
  AND token = '4mInEzbwZkBFK1xIUHp8nicbCWvDz4qKFzx3M6r8eU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}