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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '752706e9120f35c3f4a3f6041ec791aef74060a755af947e6422f273f8a7aef6' 
  AND token = 'ICPFoxTH5U5HSE3QA0TIWdPnGeFu3jxDiZrlyFAZuMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}