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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '097bdffa8cc5cd20c43d28ed9d4daf374aba15d59fe5cff00e6629cb50de3301' 
  AND token = 'esUfru045ZlSiHMt+MsxS5MsNYOXzznHVcnPEifsoeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}