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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e05139af81a832f229306910b7133b8368cf2922b20e74f89cefa4bc5cda66c' 
  AND token = 'bv5shOO0vZovXpbMQXNdx9v/nnzQyiUMzUUl/wleUdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}