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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2fca7e6e55383da0c3cba4a3e8d38b80fa8990d30c93fb14c1518aa798d0007' 
  AND token = '+AXrDe7aRsrRum4+xo8xwtkx8M22qrLOoneR643U91Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}