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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba621dba687e82f51f628e3cea2470adde5c30ccbbf1bf7fa1a34df332779657' 
  AND token = 'WJbC6izt2LlUMybXSdSbgfP2WfpvHHcL8Jh2sLPA500=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}