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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '719cfad37a3b0a1815ac0a5165b010ed30916985aa9e955848ab7f2314f4a261' 
  AND token = 'HGg9wT3ex04LDwnJeC5WmbMtiEkhfjKSlAQq1P9yxrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}