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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63465ea8dd098cbde0dfd4821d0f8073274108f247807214c2d1976fef01a5e6' 
  AND token = '0jWnSDlYk3Ao3vUY5gq8lnWdgvDOfiZDa/Plyl/i5IE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}