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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eaf78440498de63120e8b998964a65cb760dbb4b359ee572ec50e07f4840bb4' 
  AND token = '5Z5ozCzzdqe+EHZysgWpYZ6Q9O/HoZl7UBa8C8NZqkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}