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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '740d9c82d643cfb4b93f681d7532138b55ce2d021c85133ef4622e2bfa2846f8' 
  AND token = 'T7gIPUbkdn9N6vMIQ6Ksv0Dy8+4eyvuqu3xGjRXnH9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}