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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39b1f0c36f9fd356f21f2a9a8ff36bd0f870f4c02427f5dfbda98a48daa96e39' 
  AND token = 'A7QadUIntXn4re2NUtoZJ/QtTsoSvxgDx6UxOGBWJzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}