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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6af26586a2b09cce8a7aaf834816c180cab92f65e8d4b15bba1ff7eecfe74494' 
  AND token = 'HqOVdqzRy+JAAeb9ugkPng5pYjM4Sio+XZ1/gj1naXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}