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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1c10c1d5a24646016e88d996e78f9582bb5acf41d6007cd6125c31b0b752fb1' 
  AND token = 'oPElSIdcvkK7ZU9FXZ0mIbzlNEOoO4K9kf0iJnSS6AM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}