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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2b4b3f303da522d72c5d8491387eb188a23e7f4f4e901556c99bfe07d6106b5' 
  AND token = 'sF7nfi4/O0o//QRoSgILOUQE6Ycvm8vs5YTsLDlRaDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}