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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '768f079f8e78a6d8e4541a7ed8f5b54673398041c1cf81d07e5f64d29e83828f' 
  AND token = 'ZSczItbgBSq7geraUx2spOtctlsunGvm3xMino45hCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}