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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '305c48b89a12b3e512892012329409561a1cb1762dedebb84209b9afda504fa9' 
  AND token = 'moWMk1gp4xtqclBNXZCTEbPEhqbYlV+h4oPdPDQ/vRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}