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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18e1b9412bedce0a5e62f32ed94aa8d349fbb79d0b35ce6e3fa5c640c008f739' 
  AND token = 'U6ROF+VlnilkgE5NqsR1lh5YHE5YOkLIVL8yQbIquEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}