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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '655d605c27ab6e1571858e216cb52b69795f336056868fcc1d71c96512ebd8f7' 
  AND token = 'cAGI5H5xfqT1f1GhelZRvtZt5hB4oYFcmWKACuky9WQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}