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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54105c01108788b5b452c803a9504ee50286ea7c53aa0f7b9cb7557fd53c99ab' 
  AND token = 'Ppj72KlBgDv7uq0WRxPo7+cGjE1qKZqjkycNhAbM6Og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}