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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '280ed008182d8ff517ee33814227e20a40dc16a8b3759437d7f4d5bc42a86fbd' 
  AND token = 'ENoJlkzA1JHlH/9Abs2M7d+MgGk4CHq2FJnyupkAhbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}